Cytomegalovirus Retinitis: The Neglected Disease of the AIDS Pandemic
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منابع مشابه
Cytomegalovirus Retinitis: The Neglected Disease of the AIDS Pandemic
Neglected Diseases C ytomegalovirus (CMV), a member of the herpesvirus family, was a familiar cause of blindness and death in patients with advanced AIDS in Western countries prior to the introduction of highly active antiretroviral therapy (HAART). CMV retinitis then occurred in roughly one-third of patients with AIDS, and accounted for over 90% of cases of HIV-related blindness [1]. Extraocul...
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Cytomegalovirus retinitis is common in adults with AIDS but has been reported infrequently in children with perinatally acquired HIV infection. The cases are presented of two infants with vertically acquired HIV infection who developed disseminated cytomegalovirus infection and retinitis, and who posed difficult management issues.
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Cytomegalovirus (CMV) shares many properties with other members of the herpesvirus family it exhibits latency, reactivates under suitable conditions to cause human disease, and it is incurable. CMV is the primary opportunistic viral infection in the immunosuppressed person and gives rise to a wide spectrum of disease. CMV is a major cause ofmorbidity and mortality among patients with AIDS, and ...
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ژورنال
عنوان ژورنال: PLoS Medicine
سال: 2007
ISSN: 1549-1676
DOI: 10.1371/journal.pmed.0040334